CanCOLD Study

The objectives are to characterize COPD (mild to severe) among a random sample of Canadians, and patient response to disease (link of structural/physiological, clinical variables and health perception) taking into account lifestyle risk factors (not only smoking but subsequent modifiable risk factors), contextual factors (such as age and sex) and associated co-morbidities (cardiovascular diseases, osteoporosis, anxiety and depression, etc).

This will be a great asset to shift from management of a single risk factor (tobacco control) to total COPD risk management. The results of the study will greatly help to assist decision makers in developing policies to improve the diagnosis, the management of COPD and to optimize health care services use.

A total of ~2000 subjects will be sampled, ~1000 men and women, from ≥9 sites. 250 subjects per site will be selected. Sampling will be stratified by sex and stage of the disease:

  • Subjects with significant airflow obstruction and COPD moderate–severe;
  • Subjects with mild or early disease;
  • Subjects at risk for COPD (smoker with airflow obstruction);
  • Subjects non-smoker and free of airflow obstruction.